Everything about Bolus Medicine totally explained
In medicine, a
bolus (from
Latin, ball) is the administration of a
medication,
drug or other compound that's given to raise
blood concentration to an
effective level. The administration can be given
intravenously, by
intramuscular or
subcutaneous injection.
Bolus placement
The placement of the bolus depends on the systemic levels of the contents desired throughout the body. An intramuscular bolus is used in the administration of
vaccines to allow a slow release of the antigen to stimulate the body's
immune system and allow time to develop
antibodies. Subcutaneous injections are used by
heroin addicts (called 'skin popping', referring to the bump formed by the bolus of heroin), to sustain a slow release that staves off
withdrawal symptoms without producing
euphoria.
A bolus delivered directly to the veins through an
intravenous drip allows a much faster delivery which quickly raises the concentration of the substance in the blood to an effective level. This is typically done at the beginning of a treatment or after a removal of medicine from blood (for example through
dialysis).
Diabetes
Diabetics and health care professionals use bolus to refer to a dosage of fast-acting
insulin with a meal (as opposed to
basal rate, which is a dose of slow-acting insulin or the continuous pumping a small quantity of fast-acting insulin to cover the
glucose output of the
liver).
Veterinary medicine
In
veterinary medicine a
bolus is a large time-release tablet that stays in the
rumen of
cattle,
goats and
sheep.
Further Information
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